33 NEET previous-year questions on Cell Cycle and Cell Division, each with the correct answer and a step-by-step solution. Sourced directly from official NEET papers across every booklet code.
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G 0 and G 1
G 1 and S
Only G 2
G 2 and M
Solution
The amount of DNA is 4C during the G2 phase, after DNA replication in the S phase and before the onset of mitosis. NCERT XI chapter Cell Cycle and Cell Division states that DNA content doubles during the S phase and remains at 4C during G2, so option (c) is correct.
Amount of DNA-doubles in each cell
Amount of DNA remains same in each cell
Chromosome number is increased
Amount of DNA is reduced to half in each cell
Solution
In the 'S' phase of the cell cycle, DNA replication occurs, doubling the amount of DNA in each cell. NCERT XI chapter Cell Cycle and Cell Division states that DNA synthesis is a key event in the S phase, so option (a) is correct.
Telomere of the chromosome
Kinetochore of the chromosome
Centromere of the chromosome
Kinetosome of the chromosome
Solution
Kinetochore of chromosomes facilitates the attachment of spindle fibre (chromosomal fibre) and the poles. www.vedantu.com 51
Pachytene
Leptotene
Zygotene
Diplotene
Solution
In pachytene recombination nodule is formed after which crossing over occurs.
Spindle fibres
Disappearance of nucleolus
Chromosome movement
Synapsis
Solution
Synapsis is pairing of homologous chromosomes which occurs during meiosis but it is absent in mitosis.
Aneuploidy
Polyploidy
Somaclonal variation
Polyteny
Solution
Polyploidy cells have a chromosome number that is more than double the haploid number.
Condensation → nuclear membrane disassembly → crossing over → segregation → telophase
Condensation → nuclear membrane disassembly → arrangement at equator → centromere division → segregation → telophase
Condensation → crossing over → nuclear membrane disassembly → segregation → telophase
Condensation → arrangement at equator → centromere division → segregation → telophase
Solution
The correct sequence of events during mitosis would be as follows (i) Condensation of DNA so that chromosomes become visible occurs during early to mid-prophase. (ii) N uclear membrane disassembly begins at late prophase or transition to metaphase. (iii) Arrangement of chromosomes at equator occurs during metaphase, called congression. (iv) Centromere division or splitting occurs during anaphase forming daughter chromosomes. (v) Segregation also occurs during anaphase as daughter chromosomes separate and move to opposite poles. (vi) Telophase leads to formation of two daughter nuclei.
Chromosomes will not condense
Chromosomes will be fragmented
Chromosomes will not segregate
Recombination of chromosome arms will occur
Solution
Anaphase Promoting Complex (APC) is a protein necessary for separation of daughter chromosomes during anaphase. If APC is defective then the chromosomes will fail to segregate during anaphase.
Diakinesis
Diplotene
Pachytene
Zygotene
Solution
During diplotene, the homologous chromosomes begin to separate from each other, though they remain connected at chiasmata. NCERT XI chapter Cell Cycle and Cell Division describes this as the stage where chiasmata formation is completed and homologous chromosomes start to repel each other, so option (b) is correct.
Aristotle
Rudolf Virchow
Theodore Schwann
Schleiden
Solution
Factual- NCERT
Cornea consists of dense matrix of collagen and is the most sensitive portion of the eye.
Cornea is an external, transparent and protective proteinaceous covering of the eye – ball.
Cornea consists of dense connective tissue of elastin and can repair itself.
Cornea is convex, transparent layer which is highly vascularized.
Solution
Cornea is white fibrous connective tissue and very sensitive due to good nerve supply
Deletion of GGU from 7th, 8th and 9th positions
Insertion of G at 5th position
Deletion of G from 5th position
Insertion of A and G at 4 th and 5 th positions respectively
Solution
Ref. XII NCERT Chapter- 06, Page No. 114 If GGU is removed from the given mRNA, one amino acid coded by this codon is not incorporated in the polypeptide, rest all codon will not change.
Pachytene
Zygotene
Diplotene
Leptotene
Solution
The synaptonemal complex dissolves during diplotene, leading to the separation of homologous chromosomes while they remain connected at chiasmata. NCERT XI chapter Cell Cycle and Cell Division describes this event in the prophase I of meiosis, so option (c) is correct.
DNA synthesis or replication takes place.
Reorganisation of all cell components takes place.
Cell is metabolically active, grows but does not replicate its DNA.
Nuclear Division takes place.
Solution
During the G1 phase, the cell is metabolically active and grows, but DNA replication does not occur. NCERT XI chapter Cell Cycle and Cell Division states that DNA synthesis occurs in the S phase, not G1, so option (c) is correct.
M phase
G 1 phase
S phase
G 2 phase
Solution
Cells can exit the cell cycle and enter the quiescent stage (G 0 ) at the end of the G 1 phase. NCERT XI chapter Cell Cycle and Cell Division describes G 0 as a stage where cells are not preparing for division and can remain for long periods, so option (b) is correct.
(iii) (iv) (i) (ii)
(iv) (iii) (ii) (i)
(i) (ii) (iv) (iii)
(ii) (iv) (iii) (i)
Solution
- Zygotene is characterized by the formation of the synaptonemal complex (synapsis).
- Pachytene involves crossing over between homologous chromosomes.
- Diplotene is marked by the appearance of chiasmata and the beginning of chromosome desynapsis.
- Diakinesis is the stage where chiasmata move to the ends of the chromosomes (terminalization).
Metaphase I
Metaphase II
Anaphase II
Telophase II
Solution
The division of the centromere occurs during anaphase II, when sister chromatids separate and move to opposite poles. NCERT XI chapter Cell Cycle and Cell Division describes this event as a key feature of anaphase II, so option (c) is correct.
Metacentric
Telocentric
Sub-metacentric
Acrocentric
Solution
When the centromere is located in the middle of the chromosome, resulting in two equal arms, the chromosome is classified as metacentric. NCERT XI chapter Cell Cycle and Cell Division describes this classification, so option (a) is correct.
(iii) (ii) (i) (iv)
(iv) (ii) (iii) (i)
(iv) (i) (ii) (iii)
(ii) (iv) (iii) (i)
Solution
- S phase: DNA replication occurs (iv)
- G2 phase: Proteins are synthesized in preparation for mitosis (i)
- Quiescent stage: Cells in an inactive phase (ii)
- G1 phase: Interval between mitosis and initiation of DNA replication (iii)
8
16
4
32
Solution
During the S phase of mitosis, DNA replication occurs, doubling the number of chromosomes. If the number of chromosomes at G1 phase is 8, after S phase, the number of chromosomes will be 16, so option (b) is correct.
Leptotene
Zygotene
Diakinesis
Pachytene
Solution
Diakinesis is characterized by the terminalization of chiasmata, where the chiasmata move to the ends of the chromosomes. This is a distinctive feature of the late prophase I stage, as described in NCERT XI chapter Cell Cycle and Cell Division, so option (c) is correct.
S-phase
Prophase
Metaphase
G 2 phase
Solution
The centriole undergoes duplication during the S-phase of the cell cycle, when DNA replication also occurs. NCERT XI chapter Cell Cycle and Cell Division states that centriole duplication is a part of the S-phase, so option (a) is correct.
Spindle fibres attach to kinetochores of chromosomes
Movement of centrioles towards opposite poles
Pairing of homologous chromosomes
Coiling and condensation of the chromatids
Solution
Pairing of homologous chromosomes occurs during prophase I of meiosis. Coiling and condensation of chromatids, spindle fibres attachment to the kinetochores a nd movement of centrioles towards opposite poles occur in both mitosis and meiosis. - 43 - NEET (UG)-2022 (Code-Q1)
Synaptonemal complex
Bivalent
Sites at which crossing over occurs
Terminalization
Solution
Pachytene stage of meiosis is characterised by the appearance of recombination nodules, the sites at which crossing over occurs between non sister chromatids of homologous chromosomes. - 48 - NEET (UG)-2022 (Code-Q1)
All the chromosomes lie at the equator at metaphase
Spindle fibres attach to centromere of chromosomes
Chromosomes decondense at telophase
Splitting of centromere occurs at anaphase
Solution
Spindle fibres attach to the kinetochores of chromosomes. Kinetochores are the disc shaped structures present on sides of primary constriction or centromere of chromosomes.
Diakinesis
Zygotene
Pachytene
Diplotene
Solution
Recombination nodules appear during pachytene, a substage of prophase I in meiosis. NCERT XI chapter Cell Cycle and Cell Division describes pachytene as the stage where crossing over occurs, leading to genetic recombination, so option (c) is correct.
G₂ phase
M phase
S phase
G₁ phase
Solution
DNA replication occurs during the S phase of the cell cycle, when the genetic material is duplicated. NCERT XI chapter Cell Cycle and Cell Division specifies that the S phase is dedicated to DNA synthesis, so option (c) is correct.
Telophase
Metaphase I
Metaphase II
Anaphase II
Solution
The division of the centromere occurs during anaphase II, when sister chromatids separate and move to opposite poles. NCERT XI chapter Cell Cycle and Cell Division describes this event as a key feature of anaphase II in meiosis, so option (d) is correct.
Statement I is incorrect but Statement II is correct.
Both Statement I and Statement II are correct.
Both Statement I and Statement II are incorrect.
Statement I is correct but Statement II is incorrect.
Solution
Statement I is incorrect because cells in G₀ phase are metabolically active but have exited the cell cycle. Statement II is correct as centrosome duplication occurs during the S phase, as per NCERT XI chapter Cell Cycle and Cell Division. Therefore, option (a) is correct.
Both Statement I and Statement II are true
Both Statement I and Statement II are false
Statement I is true but Statement II is false
Statement I is false but Statement II is true
Solution
• During leptotene stage the chromosomes become gradually visible under the light microscope. • The beginning of diplotene is recognised by the dissolution of the synaptonemal complex and the tendency of the recombined homologous chromosomes of the bivalents to separate from each other except at the site of crossover. Thus both statement I and II are correct.
A-IV, B-II, C-III, D-I
A-I, B-II, C-IV, D-III
A-II, B-IV, C-I, D-III
A-IV, B-III, C-II, D-I
Solution
(A) Diakinesis – Completion of terminalisation of chiasmata (B) Pachytene – Appearance of recombination nodules (C) Zygotene – Synaptonemal complex formation (D) Leptotene – Chromosomes look like thin threads A-II, B-IV, C-I, D-III - 65 - NEET (UG)-2024 (Code-Q1)
C-E-D-A-B
E-B-D-A-C
B-D-E-A-C
E-C-A-D-B
Solution
The correct sequence of stages of cell division is ) Gap 1 phase Synthesis phase Gap 2 pha (E) ( se C) (A →→ Karyokinesis Cytokinesis (D) (B) →→ The correct sequence will be → E → C → A → D → B
To separate the chromosomes
To synthesize new DNA
To repair damaged DNA
To regulate cell growth
Solution
During mitosis, spindle fibre get attach to the kinetochores of the chromosome and help in the separation of the chromosome.
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