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Cell: The Unit of Life

Cell: The Unit of LifeNEET Botany · Class 11 · NCERT Chapter 6

8 interactive concept widgets for Cell: The Unit of Life. Drag any slider, change any number, and watch the formula and the answer update live. Built so you understand how each NEET problem actually works, not just the final number.

Prokaryotic vs eukaryotic cell

Compare every NEET-tested difference between prokaryotic and eukaryotic cells: nucleus, ribosomes, organelles, DNA, mesosome, and more.

Prokaryotic vs Eukaryotic cell comparison

Switch between the two cell types to see every difference NEET tests.

Prokaryotic cell
Eukaryotic cell
Show NEET-important only
FeatureProkaryoteEukaryote
Nuclear membraneAbsentPresent
Membrane-bound organellesAbsentPresent
Ribosome type70S (50S + 30S)80S (60S + 40S)
Cell size1–10 µm (smaller)10–100 µm (larger)
DNA formCircular, no histoneLinear, with histones
Cell wallPeptidoglycan (bacteria)Cellulose (plants) / Absent (animals)
Nucleoid / NucleusNucleoid (no membrane)True nucleus
PlasmidPresentAbsent (usually)
MesosomePresentAbsent
Mitosis / MeiosisAbsent (binary fission)Present
Pili / FimbriaePresentAbsent
ExamplesBacteria, Cyanobacteria (BGA)Plant, Animal, Fungi, Protista cells

★ = high-frequency NEET comparison point

Prokaryotic examples

Escherichia coli

Gram-negative bacterium, common in gut

Streptococcus

Spherical bacteria (cocci), cause throat infections

Nostoc

Cyanobacterium (blue-green alga), fixes nitrogen

Mycoplasma

Smallest known cell; NO cell wall; PPLO

Try this

  • Which NEET trap: Mycoplasma is prokaryotic (bacteria) but has NO cell wall. It is the smallest known cell.

Plasma membrane: fluid mosaic model

Click each membrane component (phospholipid bilayer, integral proteins, peripheral proteins, cholesterol, glycoproteins) to see its structure and NEET significance.

Plasma membrane: fluid mosaic model

Click each component to learn its structure and NEET importance.

Extracellular fluidCholIntegralPeriph.Glycoprot.Cytoplasm

Phospholipid bilayer

Two layers of phospholipid molecules. Each molecule has a hydrophilic (water-loving) head and two hydrophobic (water-fearing) fatty acid tails. The heads face outward (toward water); the tails face inward (away from water). This creates a stable bilayer.

NEET focus: The bilayer arrangement (heads out, tails in) is responsible for the "fluid" nature of the membrane. Phospholipids can move laterally within each layer.

Key facts for NEET

Proposed by Singer and Nicolson in 1972

"Fluid" = phospholipids move laterally within each layer

"Mosaic" = proteins scattered like tiles in a mosaic

Earlier model: Danielli-Davson sandwich model (1935): protein-lipid-protein

Membrane thickness: approximately 7.5–10 nm

Selectively permeable: small nonpolar molecules (O2, CO2) pass freely; ions and large polar molecules need transport proteins

Try this

  • Which model came BEFORE fluid mosaic? The Danielli-Davson 'sandwich' model (1935) proposed a protein-lipid-protein layered structure. Singer-Nicolson (1972) replaced it with the fluid mosaic model.

Cell organelles: plant vs animal explorer

Switch between plant and animal cells, then click any organelle to see its structure, function, and NEET focus. Covers nucleus, mitochondria, ER, Golgi, chloroplast, vacuole, centriole, and more.

Cell organelles: plant vs animal cell explorer

Switch cell type, then click any organelle to see its structure, function and NEET focus.

Plant cell
Animal cell
Cell wall
Plasma membrane
Nucleus
Mitochondria
Chloroplast
Endoplasmic reticulum (ER)
Golgi apparatus
Vacuole
Ribosome
Plastid (other types)

NucleusPlant + Animal

FUNCTION

Controls cell activities. Contains hereditary information (DNA). Site of DNA replication and RNA transcription.

STRUCTURE

Nuclear envelope (double membrane, nuclear pores), nucleoplasm, chromatin (euchromatin + heterochromatin), nucleolus (rRNA synthesis).

NEET focus: Mature RBCs (erythrocytes) in mammals: NO nucleus. Nucleolus disappears during cell division. Euchromatin = light staining, active; heterochromatin = dark, inactive.

Plant cell has but animal cell lacks:

Cell wall, chloroplasts, large central vacuole, plasmodesmata, plastids

Animal cell has but plant cell lacks:

Centrioles, lysosomes (generally), small/absent vacuoles

Try this

  • NEET trap: Mature mammalian RBCs (red blood cells) have NO nucleus and NO mitochondria. Sieve tubes in plants also lose their nucleus when mature.

Endomembrane system: ER, Golgi, Lysosomes

Follow the flow: RER synthesizes proteins, vesicles go to Golgi, Golgi modifies and sorts, trans face releases lysosomes and secretory vesicles. Understand what is and is not part of the system.

Endomembrane system: ER, Golgi, Lysosomes, Vacuoles

Click each station to understand how proteins and lipids travel through the endomembrane network.

RER

SER

Golgi

Lysosome

Vacuole

Rough ER (RER)

Rough ER has ribosomes attached to its cytoplasmic face, giving it a "rough" texture under electron microscopy. It synthesizes proteins that will be secreted from the cell, inserted into the plasma membrane, or targeted to the Golgi apparatus or lysosomes. Proteins enter the ER lumen as they are synthesized (cotranslational translocation) and undergo initial folding and glycosylation.

Ribosomes on surface
Cisternae (flattened sacs)
Continuous with outer nuclear membrane
Sends vesicles to Golgi

NEET focus: RER = ribosomes on surface + protein synthesis. Ribosomes on RER are 80S. Outer nuclear envelope membrane is continuous with RER. "Rough" because of ribosomes.

NOT part of endomembrane system:

Mitochondria:

Has own DNA and 70S ribosomes; semi-autonomous. Origin: endosymbiotic.

Chloroplast:

Has own DNA and 70S ribosomes; semi-autonomous. Origin: endosymbiotic.

Peroxisomes:

Not derived from ER or Golgi; originate by division of pre-existing peroxisomes.

Try this

  • Most-tested NEET point: Which organelle is NOT part of the endomembrane system? Answer: Mitochondria and Chloroplasts (they have their own DNA and ribosomes).

Mitochondria vs chloroplast: semi-autonomous organelles

Explore internal structure of both organelles (cristae vs thylakoids, matrix vs stroma, F0-F1 particles vs photosystems) and compare them side-by-side.

Mitochondria vs Chloroplast: semi-autonomous organelles

Compare both organelles and explore their internal structures. Both are semi-autonomous and have 70S ribosomes.

Mitochondria
Chloroplast

Mitochondria structure: click any part

Outer membrane
Inner membrane (cristae)
Intermembrane space
Matrix
F0-F1 particles

Side-by-side comparison

Show all rows
FeatureMitochondriaChloroplast
Found inAll eukaryotic cells (plant + animal)Plant cells and algae only
FunctionATP synthesis (cellular respiration)Photosynthesis
Inner membrane featureCristae (infoldings)Thylakoids stacked into grana
Internal fluidMatrix (inside inner membrane)Stroma (around thylakoids)
Key enzyme complexF0-F1 ATPase on inner membranePhotosystems I and II in thylakoid
DNA typeCircular (naked, no histone)Circular (naked, no histone)
Ribosome type70S (50S + 30S)70S (50S + 30S)
Autonomous?Semi-autonomousSemi-autonomous

Try this

  • Both mitochondria and chloroplasts have 70S ribosomes, circular DNA, and double membranes. This supports the endosymbiotic theory: they were once free-living bacteria that were engulfed by an ancestral eukaryotic cell.

Ribosomes: 70S vs 80S subunits

See the exact subunit composition of 70S and 80S ribosomes, where each type is found, and why Svedberg units are not additive.

Ribosomes: 70S vs 80S, subunits, locations, and NEET traps

Switch between 70S and 80S to see subunit composition, locations, and why Svedberg units are not additive.

70S ribosome
80S ribosome

50S

30S

= 70S

Large subunit: 50S

rRNA: 23S + 5S

Proteins: ~34

Small subunit: 30S

rRNA: 16S

Proteins: ~21

70S ribosome: key facts

Found in: prokaryotes (bacteria), mitochondria, chloroplasts

Large subunit: 50S (contains 23S rRNA + 5S rRNA + ~34 proteins)

Small subunit: 30S (contains 16S rRNA + ~21 proteins)

50 + 30 = 70S (NOT 80): S units are not additive

Antibiotics that target 70S: streptomycin, erythromycin, chloramphenicol

This is why antibiotics kill bacteria but NOT our cells (our cytoplasmic ribosomes are 80S)

Where each type is found:

Prokaryote cytoplasm: 70S
Mitochondria matrix: 70S
Chloroplast stroma: 70S
Eukaryote cytoplasm (free): 80S
Rough ER surface: 80S

Why S units are NOT additive:

Svedberg units (S) measure the sedimentation rate in a centrifuge. The rate depends on mass, shape, AND density. When two subunits combine, the resulting particle has a different shape and hydrodynamic properties, so its S value is NOT the sum of the two subunits. That is why 50S + 30S = 70S (not 80S), and 60S + 40S = 80S (not 100S).

Try this

  • NEET classic: ribosomes of mitochondria and chloroplast are 70S (same as bacteria), supporting the endosymbiotic theory. Ribosomes on rough ER are 80S (they are eukaryotic cytoplasmic ribosomes temporarily attached).

Nucleus: envelope, pores, nucleolus, chromatin

Click each nuclear component in the diagram to learn its structure (double membrane, nuclear pores, nucleolus rRNA synthesis, euchromatin vs heterochromatin) and NEET importance.

Nucleus: structure and components

Click each nuclear component to explore its structure and NEET significance.

CytoplasmNuclearenvelopePoreNucleoplasmChromatinNucleolusRER
Nuclear envelope
Nuclear pores
Nucleoplasm
Nucleolus
Chromatin

Nuclear envelope

The nuclear envelope consists of two concentric unit membranes separated by a perinuclear space (10-50 nm wide). The outer membrane faces the cytoplasm and is continuous with the rough ER membrane (studded with ribosomes). The inner membrane faces the nucleus. Together they form a double-layered boundary around the nucleus.

Double membrane (outer + inner)
Perinuclear space between them
Outer membrane continuous with RER
Present only in eukaryotes

NEET focus: Nuclear envelope = double membrane. Outer membrane is continuous with RER. This means the perinuclear space is continuous with the ER lumen. Absent in prokaryotes.

Cells with no nucleus (enucleate):

Mature mammalian RBC (red blood cell):

No nucleus, no mitochondria

Sieve tube elements (phloem):

Lose nucleus at maturity; alive but enucleate

Prokaryotic cells (bacteria):

No nucleus: genetic material in nucleoid

Try this

  • NEET trap: Where does ribosome ASSEMBLY happen? In the NUCLEOLUS (inside the nucleus), not in the cytoplasm. The completed subunits are then exported through nuclear pores to the cytoplasm.

Cell biology NEET quiz: 12 questions

Scored quiz covering all cell topics: ribosome types, fluid mosaic model, endomembrane system, organelle identification, chromatin, centrioles, and nucleus.

Cell: The Unit of Life, NEET quiz

Question 1 of 12 · Topic: Ribosome

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The 50S + 30S subunits combine to form a ribosome of:

A.

80S

B.

70S

C.

100S

D.

60S

0 answered

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